Macheda burst onto the scene last year when he scored a stoppage-time winner against Aston Villa on his debut.
The teenager then scored again less than a minute into his second match for United as a second-half substitute at Sunderland.
However, Macheda has not made a league appearance this season and Sir Alex Ferguson could consider loaning the 18-year-old out in order to gain more first-team experience.
Serie A strugglers Bologna have made a move for Macheda but agent Giovanni Bia feels the Barclays Premier League champions will not agree to a move.
"Bologna have asked for him but we have to evaluate thing with Manchester United," he said.
"This afternoon I have a telephone appointment with them, but it will be difficult for them to let him go.
"If they will do it would be on loan."
Reports have also linked the Italy Under-21 international with a move to Real Zaragoza but Bia insists the Spanish club have not contacted him.
Macheda, a former youth team player at Lazio, moved to United in 2007 and signed a new four-year contract at Old Trafford last December.
Source: Manchester Evening News