Cristiano Ronaldo missed Manchester United's 4-1 defeat to Manchester City last week with a hip flexor injury.
The former Real Madrid forward opted to return to Portugal instead of travel with his teammates to the Etihad and there remain doubts over whether he will be fit to face Tottenham on Saturday.
How long is Cristiano Ronaldo out for?
Ronaldo was absent for United's visit to City at the weekend, with manager Ralf Rangnick opting to play Bruno Fernandes and Paul Pogba up front.
He last played in the goalless draw with Watford back in February and has struggled for form so far in 2022, netting just once in a 2-0 victory over Brighton.
There have been rumours of discontent in the United camp, with Ronaldo reportedly involved in a leadership dispute in the Old Trafford dressing room. There has also been talk of a move to Paris Saint-Germain.