The 20 year old will start his time at Tottenham by linking up with the Spurs' development squad.
"We are delighted to announce that we have reached agreement with Standard Liege for the signing of Zeki Fryers," a statement on Spurs' official website read.
"The young defender, capped by England at Under-16, 17 and 19 levels, began his career at Manchester United before joining Standard Liege last summer."