Readers, asked who they believe will win the Champions League, deemed Sir Alex Ferguson's men as being best equipped to win the trophy, with 25.4% of votes cast in their favour.
The outcome may come as a surprise to many as United have faltered domestically of late and look increasingly vulnerable defensively. Nevertheless, few can deny the pedigree of the Premier League champions, who even without the departed Cristiano Ronaldo can prove a match for anyone on their day.
The performances of the talismanic Wayne Rooney though, will undoubtedly be paramount to any aspirations United have of reaching a third consecutive Champions League final. In fact, if they are to be victorious they must first overcome Italian giants AC Milan and the on-loan David Beckham in what promises to be an enthralling last sixteen tie.
Chelsea were United's closest rivals in the poll and manager Carlo Ancelotti certainly has a good track record in the competition, while European Champions Barcelona, spearheaded by World Player of the Year Lionel Messi, will again pose a huge threat to any team hoping to emerge triumphant at the Bernabeu in May.