Wellbeck will not play in the away match against Norway four days earlier.
On-loan at Tottenham striker Fraizer Campbell is also included in the squad.
England U21 squad:
Goalkeepers Joe Hart, Scott Loach, Joe Lewis
Defenders Kieran Gibbs, Michael Mancienne, Nedum Onuoha, Micah Richards, Andrew Taylor, Steven Taylor, David Wheater
Midfielders Lee Cattermole, Craig Gardner, Tom Huddlestone, Adam Johnson, Aaron Lennon, James Milner, Fabrice Muamba, Mark Noble, Jamie O'Hara, Jack Rodwell, Theo Walcott
Forwards Fraizer Campbell, Matt Derbyshire, Sylvan Ebanks-Blake, Daniel Welbeck